Although the causes of Parkinson’s disease is unknown, believed that the pathology occurs due to a set of genetic and environmental factors. Now, new research, by scientists at the University of Oxford, United Kingdom, been associated with infection by hepatitis B (HBV) and C (HCV) viruses an increased risk of developing this disease.
Genetic and environmental factors are involved in Parkinson’s disease, and it would be possible that the virus B and C hepatitis, or even treatments against these infections, influence the development of disease
The researchers studied data collected in the medical history of around 100,000 British patients that, between the years 1999 and 2011 had been diagnosed for the first time of hepatitis B (about 22,000), hepatitis C (around 48.000), chronic active hepatitis (4,000), or HIV (human immunodeficiency virus) infection (approximately 20,000).
In order to check whether there was any relationship between these infections and Parkinson’s, also analyzed the medical records of more than six million people who had requested medical assistance for many other reasons, from a knee until an intervention of cataract surgery.
HBV and HCV are viruses that increase the risk of Parkinson’s
They noted that persons who had been diagnosed of hepatitis B were 76% more likely to end suffering parkinson. Compared to the Group of people affected by some type of hepatitis treated control population for other diseases, the scientists found that if the number of expected cases of Parkinson’s among those affected by HBV was 24, the total number of diagnoses amounted to 44.
Hepatitis C infection was linked to up to 51% higher risk of developing Parkinson’s – there were a total of 73 diagnoses in this group when expected 49. In the case of those infected by HIV, autoimmune hepatitis or chronic active hepatitis, not appreciated any increase in the odds of this neurodegenerative disease.
Julia Pakpoor, Director of the study, published in Neurology, has explained that genetic and environmental factors involved in Parkinson’s disease, and that it would be possible for the viruses B and C hepatitis, or even treatments used to fight these infections, to play a role in the development of the disease. And he adds that another possibility considered is that people prone to HBV or HCV infection are also more susceptible to Parkinson’s.