A study conducted by researchers at the University Hospital in Gentofte, Denmark, has found that some anti-inflammatory consumption would be related to an increase in the risk of suffering a heart attack. This relationship is particularly evident in the case of ibuprofen (the odds increase by 31%), and diclofenac (50%). Scientists say that the results of this study support the evidence accumulated over the years on a profile of adverse cardiovascular risk associated with the use of nonsteroidal anti-inflammatory drugs (NSAIDs).
The relationship between the consumption of anti-inflammatory drugs and heart failure is especially evident in the case of ibuprofen (the odds increase by 31%) and diclofenac (50%)
To reach these conclusions, this hospital in Copenhagen researchers studied nearly 29,000 cases of Danish patients, who had suffered a cardiac arrest outside a hospital between 2001 and 2010. Of them all, close to 3,400 had taken any NSAID during the 30 days prior to the episode, being the ibuprofen most commonly used (50%), followed by diclofenac (22%).
After analyzing the results, the researchers checked how these patients who had been treated with anti-inflammatory drugs in the last month not drugs – notably ibuprofen and diclofenac, had an increased risk of heart failure early, as well as of other cardiovascular diseases such as ischemic heart disease, myocardial infarction, or heart failure.
Risk of anti-inflammatory drugs for cardiovascular patients
Anti-inflammatory drugs not drugs (NSAIDs) are among the most widely used around the world. According to the study, more than 50% of the Danish adult population had at least one prescription of an NSAID during 1997-2005, and used nearly 30 million adults in the United States in a way regular in 2010. However, medical recommendations of recent years already warned of the dangers that it involves the abuse of these drugs.
Thus, in April 2015, the Spanish Agency of medicines and health products (AEMPS) explained the risk at high doses (2,400 milligrams per day) ibuprofen consumption had in people affected by serious cardiovascular disease, although it gave that normal use (up to 1200 mg/day) has not had been associated so far with increases in the risk of cardiovascular.